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Test tells how fast vitamins dissolve
By Richard Harkness McClatchy Newspapers - 02/27/2007
Q: I’ve heard that vitamins in tablet form do not digest properly. They say if you put them in a glass of water or vinegar, and they don’t dissolve in 30 minutes, they are digesting in our intestines, which means we are not getting any value from the vitamins. I work in the holistic health department at a natural food store. My manager says this is not a fair test. Can you provide any information on this?
A:A brief anatomy lesson is helpful. The first stop for things you swallow is the stomach, which serves as a reservoir that allows digestion (food breakdown) to take place gradually. Stomach contents empty into the duodenum, which empties into the longer tract of the small intestine, made up of the jejunum and ileum.
It is during the trek through the small intestine that most digested foods and dissolved pills are absorbed into the body.
I think the primary issue you’re concerned with is how well vitamin tablets disintegrate (break apart) and dissolve. This is, indeed, critical. Tablets that fail to dissolve properly may not release their contents into the small intestine in time for absorption to occur.
Tablet or caplet forms are more likely to have disintegration problems than capsules and chewable tablets.
In an official laboratory disintegration test, a pill is continuously agitated in an acidic solution (mimicking the stomach) for up to 45 minutes.
During this time, it should fall apart.
ConsumerLab.com, a company that tests dietary supplements, won’t approve products that fail this test.
Do-it-yourselfers might wish to try the following unofficial home test provided by ConsumerLab.com. As the company points out, it isn’t foolproof, but it does yield helpful information.
Heat ˝-cup of vinegar (acetic acid) in a heat-safe cup on the hot-plate portion of a coffee machine to 98.6 degrees Fahrenheit (body temperature). For a quick check of the temperature, use an instant-read thermometer, and don’t allow it to rest on the bottom of the cup where heat is most intense, giving a false reading.
Place a pill in the cup, then stir continuously for 30 to 45 minutes, without hitting the pill and keeping the temperature near 98.6 degrees. If necessary, move the cup on and off the heat to maintain a constant temperature.
Uncoated or thinly coated products should disintegrate in about 30 minutes; gelatin-coated and hard-coated products may require the full time.
Note: This test may not work with ‘‘time-release’’ or ‘‘sustained-release’’ products. And be aware that ‘‘chewable’’ products are meant to be broken down by chewing and ‘‘enteric-coated’’ products should not fully break apart in this test since they are supposed to release their ingredients farther down the gut in the intestines.
By the way, a few of the multivitamin-multimineral products recently tested by ConsumerLab.com flunked the official disintegration test. Visit the Web site to learn more.
Richard Harkness is a consultant pharmacist, natural medicines specialist, and author of eight published books.
Write him at 1224 King Henry Drive, Ocean Springs, MS 39564; or rharkn@aol.com. Selected questions will be used in the column.) ——— (c) 2007, The Sun Herald (Biloxi, Miss.).
Visit The Sun Herald Online at http://www.sunherald.com/ Distributed by McClatchy-Tribune Information Services.
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